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隋森芳 博士

教授,博士生導師
中科院院士

1964-1970 清華大學精密儀器系,學士
1978-1981 清華大學工程物理系,碩士
1985-1988 德國慕尼黑工業大學生物物理所,博士
1989-1991 清華大學生物科學與技術系,副教授
1991.1-至今 清華大學生命科學學院(2009年9月以前為生物科學與技術系),教授、博導

● 研究興趣、領域:

我們利用冷凍電子顯微學,結合生物化學、生物物理學和細胞生物學等技術手段,研究:
(1)蛋白質復合體、復雜蛋白質機器和膜蛋白的結構、功能與工作機制;
(2)囊泡運輸中的分子機制,蛋白質與膜脂的相互作用,生物膜與重大疾病的關系。

 

● 代表性論文:

1. Ma J, You X, Sun S, Wang X, Qin S, Sui SF*. (2020) Structural basis of energy transfer in Porphyridium purpureum phycobilisome. Nature, 579(7797):146-151.
2. Pi X, Zhao S, Wang W, Liu D, Xu C, Han G, Kuang T*, Sui SF*, Shen JR*. (2019) The pigment-protein network of a diatom photosystem II-light-harvesting antenna supercomplex. Science, 365(6452). pii: eaax4406.
3. Huang X, Sun S, Wang X, Fan F, Zhou Q, Lu S, Cao Y, Wang QW, Dong MQ, Yao J, Sui SF*.(2019)Mechanistic insights into the SNARE complex disassembly. Sci Adv.,5(4).
4. Qin X, Pi X, Wang W, Han G, Zhu L, Liu M, Cheng L, Shen JR, Kuang T*, Sui SF*. (2019) Structure of a green algal photosystem I in complex with a large number of light-harvesting complex I subunits. Nat Plants, 5(3):263-272.
5. Pi X, Tian L, Dai HE, Qin X, Cheng L, Kuang T, Sui SF*, Shen JR*. (2018) Unique organization of photosystem I-light-harvesting supercomplex revealed by cryo-EM from a red alga. Proc Natl Acad Sci USA, 115(17):4423-4428.
6. Yang X, Yang F, Wang W, Lin G, Hu Z, Han Z, Qi Y, Zhang L, Wang J, Sui SF*, Chai J*. (2018) Structural basis for specific flagellin recognition by the NLR protein NAIP5. Cell Research, 28(1):35-47.
7. Zhang J, Ma J, Liu D, Qin S, Sun S*, Zhao J, Sui SF*. (2017) Structure of phycobilisome from the red alga Griffithsia pacifica. Nature, 551(7678):57-63.
8. Sun S, Li L, Yang F, Wang X, Fan F, Yang M, Chen C, Li X, Wang HW, Sui SF*. (2017) Cryo-EM structures of the ATP-bound Vps4-E233Q hexamer and its complex with Vta1 at near-atomic resolution. Nat Commun., 8:16064.
9. Hu Z, Zhou Q, Zhang C, Fan S, Cheng W, Zhao Y, Shao F, Wang HW, Sui SF*, Chai J*. (2015) Structural and Biochemical Basis for Induced Self-propagation of NLRC4. Science, 350(6259):399-404.
10. Chang L, Liu X, Li Y, Liu CC, Yang F, Zhao J*, Sui SF*. (2015) Structural organization of an intact phycobilisome and its association with photosystem II. Cell Research, 25(6):726-737.

● 聯系方式:

電話:+86-10-62792083/62784768
E-mail: suisf@mail.tsinghua.edu.cn
Lab website: http://suilab.www.ouruidi.cn/

 

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